Alveolar Sockets Preservation Using Hydroxyapatite / Beta tricalcium Phosphate with Hyaluronic Acid (Histomorphometric study)

Alveolar atrophy following tooth extraction remains a challenge for future dental implant placement. Immediate implant placement and postextraction alveolar preservation are two methods that are used to prevent significant postextraction bone loss. The purpose of this study is to investigate the usefulness of hydroxyapatite / beta tricalcium phosphate (HA/BTCP) with hyaluronic acid (HY) for alveolar sockets preservation. Thirty-two New Zealand white rabbits were subjected to the lower left incisor extraction. The rabbits were equally divided into three groups. The extracted sockets (n = 12/group) were filled with : HA/BTCP, HA/BTCP + HY and blood clot (control). All rabbits were sacrificed for histological and histomorphometric evaluation after 4 and 8 week healing periods. The results demonstrated that all sites examined in this study displayed evidence of new bone formation. A statistically significant difference in the amount of new bone formation were found between sites that healed for an average of 8 only. The results demonstrating approximately 78%,68 % and 63% of new vital bone formation for groups grafted with HA/BTCP +HY , HA/BTCP and control group respectively after 8 weeks postoperatively. In conclusion these results exhibited that the use of hydroxyapatite / beta tricalcium phosphate with hyaluronic acid appears to be more efficient in osteoconduction when compared with of hydroxyapatite / beta tricalcium phosphate alone and could be promising strategy for preservation of alveolar sockets. [Amr ELkarargy. Alveolar Sockets Preservation Using Hydroxyapatite / Beta tricalcium Phosphate with Hyaluronic Acid (Histomorphometric study). J Am Sci 2013; 9(1): 556-563]. (ISSN: 1545-1003). http://www.jofamericanscience.org. 78